Tessara Therapeutics Pty Ltd

Tessara’s mission is to accelerate the development of new therapies for neurological diseases through the standardisation and democratisation of the neuroscience data needed to identify and prioritise the best AI leads for human clinical development. To achieve this, we will combine globally generated data from our world-first, human cell-based RealBrain® in vitro models with a cloud-based, AI data-analytics platform to make the enabling neuroscience data universally accessible. Only our RealBrain models are highly relevant to the human brain and sufficiently high-throughput to release the bottleneck presented by the increasing abundance of AI-designed drug candidates. Failing early and failing fast in drug development has never been more critical.

The brain is our most valuable asset, it shapes our memories, identity, and our engagement with the world. Tessara Therapeutics is at the forefront of a transformative wave in neuroscience, introducing an unparalleled platform that harnesses the collective power of data to reveal new dimensions in brain science.

Artificial intelligence is rapidly flooding the drug discovery funnel with a multitude of new compounds. To realise the value of this deluge of potential new drugs, we now need to match the speed and scalability of AI to test those candidates in a high-throughput, human-relevant model. This presents a significant commercial and clinical translational hurdle due to the inherent failings of current approaches to drug discovery that typically rely on animal models that often fail to reflect human physiology. At the same time, in the last two years, the US FDA and the European equivalent EMA have moved decisively to remove the longstanding mandate for testing new drugs in animals and to promote the use of human-relevant approaches. Thus, we are at the intersection of two revolutions in human medicine, and Tessara’s unique offering ideally positioned to capitalise on the opportunity.

Tessara is poised to catalyse and accelerate the advancement of drug discovery and enhance clinical trial success rates to pave the way for new therapies. Together, through the improvement of brain health, we are working to reduce incalculable human suffering and foster healthier communities worldwide.