Sothic Bioscience

Sothic Bioscience produces a novel bio-identical LAL product. This reagent plays a vital role in pyrogen testing, ensuring the safety of pharmaceuticals and med-devices. Our product (LimuleXTM) removes the declining animal source from the equation, modernizing the outdated supply chain with a better quality product. We replace the use of unsustainable animal-derived reagents with scalable production of high-quality biomolecules. We provide a 3Rs solution to this industrial problem, reducing pressure on a threatened species. This translates to huge cost savings for industry compliance.

Limulus Amoebocyte Lysate (LAL) reagent is an aqueous extract of blood cells from the Atlantic Horseshoe Crab (Limulus polyphemus), a vulnerable species. Conventional production is labour intensive, with a high cost of manufacture, inconsistent quality and seasonal raw material supply.
Continuing advances in medical devices and therapeutics are placing ever growing demand for this keystone reagent for ensuring the safety of all of these products. Meanwhile stocks of the Horseshoe Crab species are now threatened. Without innovation we can scarcely supply current demand, let alone future.

These problems are detailed further in recent articles in Popular Mechanics:
http://www.popularmechanics.com/science/health/a26038/the-blood-of-the-…

and Scientific American:
https://www.scientificamerican.com/article/medical-labs-may-be-killing-…