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PROTEIN ALTERNATIVES SL

PROTEIN ALTERNATIVES SL_logo
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Biotechnology company focused on the design and development of biomarker-based assays for early diagnosis of cancer and novel monoclonal antibodies for targeted therapy in oncology

Tres Cantos, Madrid, Spain

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  • 10

    employees

  • €180,000

    turnover

English

PROTEIN ALTERNATIVES SL

English

Protein Alternatives (ProAlt) is a Spanish biotechnology company dedicated to the development of innovative, first-in-class therapeutic antibodies for the treatment of metastatic tumors and improved liquid phase diagnostic tools for the early detection of colorectal cancer. For the treatment of colorectal and melanoma metastatic tumors, the company has developed anti-cadherin 17 (CDH17) specific monoclonal antibodies. By targeting the conserved RGD...

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Protein Alternatives (ProAlt) is a Spanish biotechnology company dedicated to the development of innovative, first-in-class therapeutic antibodies for the treatment of metastatic tumors and improved liquid phase diagnostic tools for the early detection of colorectal cancer. For the treatment of colorectal and melanoma metastatic tumors, the company has developed anti-cadherin 17 (CDH17) specific monoclonal antibodies. By targeting the conserved RGD tripeptide domain in CDH17, the therapeutic mAb acts through a novel mode of action by inhibiting integrin beta 1 activation (mediated by RGD motif in cadherin 17), thus affecting cell adhesion, proliferation and migration. In vivo proof of concept studies with the humanized lead candidate PA-0661, using a murine model of metastatic disease, showed significant improvement in survival rates of all treated animals and avoided mestastasis formation in most of them. The company is seeking financing to complete during the next two years the preclinical development of the therapeutic monoclonal antibody PA-0661. The Company also considers to increase the investment series to include Phase I/IIa clinical trials in humans. 

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Seal of Excellence
The Seal of Excellence is a quality label awarded to project proposals submitted to Horizon 2020 which succeeded a highly competitive evaluation process by independent experts, but did not received funding due to budget limits. This quality label is a guarantee for investors to find high standard project proposals from European SMEs with growth potential.
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InvestHorizon
InvestHorizon is an accelerator programme designed to facilitate the access to Series A funding for selected DEEP TECH companies.
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Access2EIC – Seal of Excellence
The Access2EIC -Seal of Excellence community aims at gathering high potential European companies that received from the European Commission a “Seal of Excellence” certificate and European equity investors. https://access2eic.eu/
1931 Members